Poloxamer-188 Adjuvant Efficiently Maintains Adaptive Immunity of SARS-CoV-2 RBD Subunit Vaccination through Repressing p38MAPK Signaling
Traditional animal vaccine adjuvants are mostly water-in-oil W/O adjuvants, which can induce higher antibody production titer, but with poor stability (oil and water separation layer).
Once the viscosity is too high, it will be much more difficult to inject causing the subcutaneous tissue lesion of designated animals and bringing safety concerns for animals of high economic value and companion animals.
Our O/W adjuvant, SUMMIT™ MT8, which contains BOTH triglycerides and mineral oil can be used with many types of antigens and high bioavailability. Stable emulsion can be formed by mixing with SUMMITTM MT8 at any ratios of 2:8 to 4:6 according to your need.more
Our O/W adjuvant, SUMMIT™ P178, which shows extreme low viscosity with low oil content can be used to mix with any types of antigens for poultry vaccines. SUMMIT™ P178 rapidly induces high antibody titer for protection with high safety. Without sophisticated homogenizing equipment, very stable vaccines are formed by imply mixing with SUMMIT™ P178 at any ratios of 2:8 to 4:6 according to your need.more