Core Technology
Veterinary Vaccine Adjuvant
Country Best has successfully produced a wide range of veterinary vaccine adjuvant products for our customers. This success is supported by professional research teams specializing in veterinary science, biochemistry, colloidal science, and other related fields. Our core technologies are based on polymer technology, emulsification technology, and encapsulation systems for protein-based materials. We are proud to apply these technologies to develop adjuvants that offer high safety, efficacy, stability, controlled release, and highly efficient immune responses. From concept and design to full-scale production, we create innovative and reliable colloidal technologies to develop adjuvant products that meets a variety of needs. Our core adjuvant technologies include:

Emulsion technology
Emulsion-type adjuvants, including water-in-oil (W/O) or oil-in-water (O/W) emulsions, have several disadvantages related to emulsification and mixing ratios, which may lead to instability or low vaccine efficacy. Our novel HLB technology maximizes the stability of O/W adjuvants across a wide range of mixing ratios without requiring sophisticated homogenizers or temperature control, thereby saving time and costs. In addition, our O/W emulsion adjuvants can be easily sterilized through membrane filtration, facilitating successful sterilization-process validation for your vaccine product.

Polymer technology
Adjuvant containing no oil or very little oil often have difficulty inducing an early immune response and maintaining long-lasting antibody titers. Our unique polymer technology comprises of biodegradable polymers formulation that appears to provide an excellent adjuvant effect for microencapsulated protein antigen. This effect may result from the controlled release of antigens and/or polymer-mediated stimulation of dendritic cells.

Dispersion and encapsulation technology
The dispersion technology we have developed increases the solubility of bulk antigens when they are mixed with our adjuvant, maximizing antigen adsorption and/or encapsulation efficiency of to achieve the required immune response.

Our Core
Our core technologists provide comprehensive adjuvant application support- from helping you select the most suitable adjuvant and develop the ideal properties required for your vaccine product to providing technical information, formulation assistance, and finally scale-up support.
